While I am reloading, I am constantly thinking of ways to make the job more efficient. I do not mind having to do 500 actions on my Single Stage Rock Chucker press. I think of ways to make the job go a bit quicker, like putting one of those yellow and black clamp things on the arm of the press so I am not bringing the ram all the way to the bottom if I am reloading short cases like .380. Shorter strokes on the handle all add up.
I figure any movement that I can eliminate makes the job go just a bit faster. When I am setting primers in four trays of 50 (dedicated Frankford Arsenal Blue Trays), I have learned to pick up one that needs priming and take the one just primed out of the shell holder and put the case in that is ready for a primer. While I am priming the current case, I am picking up the next case that needs priming and so on. It takes a bit of manual dexterity, but once you have it down, it makes things go a lot more smoothly.
When I get to the point where it even begins to feel at all monotonous, I typically stop as I realize that monotony could lead to something negatively happening (or not happening). My press and all is in the basement. I don't have kids, so whichever way I leave it, when I come back, even in two months, it is just as I left it. I do make notes on post-its to let myself know what has been done and what needs doing. So, when I start again, there is no question where I left off!
As for getting rid of a gun, I am over that. I no longer get rid of any of my guns. I got to the point where I have just what I need, nothing more, nothing less.