Because of the location of the extractor on the M-92, it will push the cartridge to the bottom of the chamber. So, if it doesn't seal well, it would be no surprise that the blowby would tend to be along one side.
I agree that 296 is NOT the best powder for this round. Especially in less than max loads. It will not burn efficiently and is probably contributing to your getting hit with particles during firing. Faster burning powder will combust MUCH better, build pressure quicker and, even if it leaks a little, will have little powder grains left to blow back at you.
Unique is probably the all-around best powder for the Colt....amoungst smokeless fans. The Holy Black is what it was invented to use and it works great. But, I understand you wanting to use smokeless for hunting...just in case you need a follow-up shot!
The Lyman 47th shows 9.3 Unique for 1100fps out of a rifle with 250grn jacketed projo. That should just about do any animal you would care to hunt with the rifle. Good luck.