jonny, I fed the data into my Powley Computer for the Krag cartridge. Keeping in mind the .30-40 is limited by SAAMI to only a 40k cup. With 165 grain bullets the ideal powder speed would be in the range of 4895, 748, and N135. With 180 grain bullets the ideal speed shifts slightly slower: RL15 and 4064. 220 grain bullets should prefer powders that are slower yet, in the range of Varget and N540. That's what the math, some of my own assumptions, and thermodynamic theory says, YMMV. The two powders you have look to be perfect for developing Krag loads, and could be used for any of your stated bullet weights.