Certaindeaf
member
I really like a 4" .357 magnum for varmints. You can blow them up or smash through a lot of meat and bone, depending on the critter. For reaching out a ways,.. never mind, they're all good, they're varmints!
But the Swift is king of the .22 centerfires.
243 is one tough customer in the varmint department, it can easly match the 22-250's ballistics downrange and can sling 100gr pills for larger varmint (aka hogs) The 25-06 is a superb dual purpose hunting rifle/splader cannon but many would say that it is simply too excessive for a purpose built varmint gun.
I like 60 grains of 3Fg pushing a patched .380 round ball from my .40 caliber flintlock on groundhogs. Hammers them out to 100 yards