I agree with the revolver idea. I have both, semi-auto and revolver. When I was looking to buy my first hand gun, I was thinking about a S&W 686 ( .357 ), but ended up buying a S&W 617 ( .22 revolver ), the best choice I ever made. Though, a 686 is a fine gun, you have much more ammo for the price with a .22, and get to shoot it thousands of times for the price of a few hundred .357's. Everyone should own a .22. The Ruger Mark II/III is a good idea, good quality and price, though there are others.
Also, the idea that you should try a bunch of guns before you buy, is very good advice. There are thousands of gun brands and models out there and each one is, at least slightly, different in feel and performance. I bought my first gun because of the feel, and to this day, it is still the gun I like to shoot most.
There are many good brands out there, Smith & Wesson (S&W), Colt, STI, Ruger, Glock, Springfield (SA), Browning, Kahr, H&K, CZ (one of my favorites), Sig, FN, Steyr, Kimber, etc.. All of these are good, even great, guns. The point is, with all these great guns to chose from, you should be able to find a good gun that feels good in your hands and offers great quality. The best one for you will be the one that fits your hands the best. With all these to choose from, you should be able to find one that works for you. Try as many as you can and buy the one that feels the best to you.
With small hands, you might want to concentrate on single-stack semi-auto's and revolvers. I have small hands also, but shoot a CZ SP-01 very comfortably, so size is not always the major factor. Some makers like Walther and SA make some guns that have interchangable backstraps which allow you to fit the grip to your hands.
To answer your direct question, Glock is a good brand and for some people is the best gun on the planet, but for others, it is the hardest gun to shoot accurately. The 23 is a .40 cal. and some people find the .40 a hard round to handle, there are many cal's that are good for self defence that have less felt recoil, 9mm, .38, .380 (maybe), others. Those that say that a .38 should be avoided are not considering every angle. I have a S&W 638 (.38 special) and feel comfortable using it for CCW, I feel no need to carry a .357. I would not want to shoot a 1 7/8" bbl 12 oz. gun in .357, done it and don't ever want to do it again.
If you are like I was before buying my first hand gun, you have hundreds of questions, and I spent over a year in forums trying to answer them. Most of my questions, I answered for my self after buying my first hand gun. I'm glad that I started with a .22 revolver.