Twenty two long rifle cartridges are one of the oldest, if not the oldest, cartridges around. At the time they were created bullets were externally lubricated. If you also notice, the bullet diameter is equal or greater than the case diameter. This older design died through natural selection around 1880’s, except for those legacy rounds that stayed within the market place.
Of course the bullets are lubricated, in fact, the whole case is lubricated. Many 22LR’s are blowback actions and need the case lubrication to keep friction between the case and chamber from stopping action cycling. This should be a “duh”, but anyone who has had sticky extraction in their bolt rifle or revolver ought to understand that the same level of extraction trouble, due to sticking cases, in a gas gun will stop it from functioning.
To continue down this path, prior to WW2 all delayed blowback designs used passive or active oiling mechanisms. Here is something future General Hatcher wrote for the Army Ordnance Magazine:
Army Ordnance Magazine, March-April 1933
Automatic Firearms, Mechanical Principles used in the various types, by J. S. Hatcher. Chief Smalls Arms Division Washington DC.
Retarded Blow-back Mechanism………………………..
There is one queer thing, however, that is common to almost all blow-back and retarded blow-back guns, and that is that there is a tendency to rupture the cartridges unless they are lubricated. This is because the moment the explosion occurs the thin front end of the cartridge case swells up from the internal pressure and tightly grips the walls of the chamber. Cartridge cases are made with a strong solid brass head a thick wall near the rear end, but the wall tapers in thickness until the front end is quiet thin so that it will expand under pressure of the explosion and seal the chamber against the escape of gas to the rear. When the gun is fired the thin front section expands as intended and tightly grips the walls of the chamber, while the thick rear portion does not expand enough to produce serious friction. The same pressure that operates to expand the walls of the case laterally, also pushes back with the force of fifty thousand pounds to the square inch on the head of the cartridge, and the whole cartridge being made of elastic brass stretches to the rear and , in effect, give the breech block a sharp blow with starts it backward. The front end of the cartridge being tightly held by the friction against the walls of the chamber, and the rear end being free to move back in this manner under the internal pressure, either one of two things will happen. In the first case, the breech block and the head of the cartridge may continue to move back, tearing the cartridge in two and leaving the front end tightly stuck in the chamber; or, if the breech block is sufficiently retarded so that it does not allow a very violent backward motion, the result may simply be that the breech block moves back a short distance and the jerk of the extractor on the cartridge case stops it, and the gun will not operate.
However this difficultly can be overcome entirely by lubricating the cartridges in some way. In the Schwarzlose machine gun there is a little pump installed in the mechanism which squirts a single drop of oil into the chamber each time the breech block goes back. In the Thompson Auto-rifle there are oil-soaked pads in the magazine which contains the cartridges. In the Pedersen semiautomatic rifle the lubrication is taken care of by coating the cartridges with a light film of wax.
Blish Principle….There is no doubt that this mechanism can be made to operate as described, provided the cartridge are lubricated, …. That this type of mechanism actually opens while there is still considerable pressure in the cartridge case is evident from the fact that the gun does not operate satisfactorily unless the cartridges are lubricated.
Thompson Sub-Machine Gun: … Owing to the low pressure involved in the pistol cartridge, it is not necessary to lubricate the case.
The Hispano-Oerlikon,was passively lubricated, and the lubrication was grease. The Oerlikon was a 20mm delayed blow back cannon, used by the US Navy from WW2 all the way through Vietnam. You can see at exactly 2:14 on this WW2 video a crew assembling belts of ammunition and a Sailor’s hand painting grease on the 20 mm Oerlikon ammunition.
http://www.youtube.com/watch_popup?v=9dR3h2HdnBQ
Basically if you dissolve the wax lubricant from your 22 LR ammunition you will have accuracy issues and if you are shooting in a blowback action, possibly extraction issues.