JMOfartO:
Please suggest to your sister, (can't tell a woman anything, I've been married almost 42 years.. Trust me on this.) that in YOUR opinion a 25cal. pistol is not necessarily the "best" choice for her.
If she is determined to get a pistol, vs a revolver, then there are a zillion 380cal. pistols on the market, and more coming daily. If the 380cal. is too "stout" for her likings, plenty of 32cal. pistols available too..
But I'm an old fart (almost 67) and from over half a century of experience with firearms, handguns in particular, I would SUGGEST a pistol of any caliber or description is not the "best" choice for someone with limited experience with firearms.
IF your sister were MY sister, daughter, granddaughter (get the picture?) I would recommend a quality 38cal. revolver. In fact I would just buy that person a Smith & Wesson J-frame (or if she insists let her use her money).
There are hundreds, heck probably thousands of good used J-frames for sale all over the place. Most of them were seldom even fired, and spent most of their time stashed away, in the same manner your sister will probably stash away whatever firearm she winds up with.
I've had J-frames of one model or another for over 40 years, and never had one to malfunction in any way.. If your sister had a J-frame all has to do is put 5 rounds in the appropriate holes in the cylinder. and then if danger comes her way, pull the trigger 5 times..
Not sure that "shoot to hurt" business makes any sense... Ok, it makes NO sense, but her brain is working the way it's working so no sense in even saying more about that.
I am willing to bet that, heaven forbid, she HAD to use a firearm in defense of her life she wouldn't be aiming for a flesh wound on the threat, she'd just be "pointing and pulling" until the threat was stopped or she was out of ammo.
I recommend you TEACH her to practice shooting from 3 yards (yep, 9') with just a point and pull method.. She will hit the target from that practice distance, and that will increase her confidence, and that's a good thing.
Don't be looking for logic in her desires, just love her for being a good sister (well, I assume she's been a good sister.. Crap if she's been a bad sister
then let her buy a 25ca. Raven and go on about your business... Just kiddn')
I'm sure someon wiser than myself (not too much required to do that) will come along with a better suggestion.
But I'm telling ya, a good revolver is hard to beat, especially for someone not "into" guns.
No offense to those who might disagree.. I could be wrong, been wrong before.
Best Wishes,
Jesse
P.S. IF your sister is determined to get a "pistol" then for her budget I'd suggest the Ruger LCP, or KelTec P3AT... There are other great choices, but the best bang for the buck (no pun intended) would probably be one of these two.