Would she consider a Taser? It meets the requirements of "hurt, but not kill" and around $300.
IIRC, some jurisdictions consider the use of a tazer to be a form of lethal force, as there have been quite a few people killed by them. They are less lethal, not nonlethal. Not sure about NC, I've never looked into it.
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To the OP, you've been pretty saturated with suggestions so far, so I won't list anymore. But I think you've got the right idea: When you go out, just do so with the idea of taking guns for a "test drive". No pressure to purchase. Get a feel for what she likes and what she doesn't. Then, you can give her guidance and some suggestions, but ultimately the decision must be hers. A gun is a lot like a pair of shoes; someone else can't tell you what you are gonna like.
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Okay, I really don't want to drift this thread but ... I gotta stand with Gryffydd.
BHP FAN, would you want to use a small .38 Special revolver against somebody with a Sig P239 or an H&K USP? What about using a small .38 Special revolver against five big guys who are about to mug you with whatever weapons they might be carrying? If you could remain level-headed, you would have about one shot per mugger until after your 15-second reload.
Sure. I shoot J-Frame .38s FAR, FAR, FAR better than equivalent sized autos. My groups with a Kel-Tec or baby Glock are measured in feet, while they are measured in inches with my 642. But I usually carry a 2" 6-shot Model 15, as I shoot it better still. Better than my 1911 in fact. So for me, it is quality over quantity, though there is certainly nothing wrong with having more ammo. But it is not the only criteria in selecting a handgun for serious purposes, IMHO. Hitting the target is a biggie, and there are still plenty of us out there that do better with the "obsolete" wheel gun. If I were armed with a little compact auto, my only hope would be to hurtle enough lead towards the BG(s) that hopefully, eventually, said BG(s) might walk into a piece of it
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And I practice revolver reloads quite a bit. I can do a revolver reload as fast or nearly as fast as an auto reload. And if you don't practice, the auto reload can be flubbed pretty badly as well, such as fumbling and dropping the mag (it is kinda slippery, after all), or even trying to shove it in backwards in the heat of the moment. Heck, I've done that once, maybe twice with my 1911 just punching holes in paper!
Tying this back into the OP, the point is your sister's mindset and training will do a lot more to save her in a serious encounter than the platform she is carrying, assuming it functions reliably. As someone else said earlier, a 25 ACP is still many, many times better than "please don't hurt me". Taking the CCW class is a great place to start.
Drop me a PM sometime. I live in NC as well, so if you happen to be nearby and my schedule allows (December is pretty hectic for us all), maybe I can let your sister try out a few of my guns.