sixgunner455--I apologize to you--or anyone else--who took my comment as an admonition to man-up--it was not that kind of entreaty: it was an attempt to encourage people to do what they need to do to toughen their hand.
Elsewhere, I have elaborated on what I did: I could barely stand a cylinder-full of 110-gr. standard pressure 38-Special loads in my M&P340 when I started shooting it. Barring personal health issues such as arthritis (which I, too, have), simply doing grip exercises and shooting a lot--working up reloads I could tolerate--got me to a much better spot.
I don't think it really is about 'manning up,' and again, I apologize. Now, less we divert this thread, if you want to discuss these two posts further, PM me.
Jim H.