If you only load each powder into 1 caliber, with 1 projectile, at 1 charge weight, go ahead and load it all. I have a half dozen pistol powders, they cross over between 4 calibers, 20+ projectiles, and a few different charge weights.
Rifles are even worse. Just for .308 I have 17 different projectiles, 3 different primers, 5 different types of brass, 2 types of dies, 8 powders, and about 100 recipes. To keep any amount of loaded rounds of each combo on the shelf just isn't practical. Keep 250 of 3 different "go to" loads for my target gun, and 60 hunting rounds.
But then again, I'm not afraid of poop hitting fans, I just like to shoot and experiment with different rounds and see what they do. So for me, as long as I have 2 mags of +P+ 9mm for my nightstand gun, components to load while I watch TV, and enough shotgun shells to last me until the next pallet turns up, I'm happy,