1. Ruger Single Six, stainless steel, with .22 WMR and .22 LR cylinders. (Mine does not yet have a .22 LR cylinder.)
2 & 3. 1911 pistols, full-Government-sized, all-steel, .45 ACP, with a .22 upper unit. (I have three Les Baers, and a Detonics. Always looking at Colts.)
4. Glock G17 pistol, Gen4, 9mm, with a .22 LR conversion unit.
5. US Firearms Single Action, .45 Colt. This is a slightly more-robust design copy of the Colt SAA.
I am glad that this is just a thought exercise. If I really like a particular handgun, I want to have a “pair and a spare.” Having three of each favored handgun does start adding up. I actually have four 1911 pistols, quite a few Glocks, and several nice single-action sixguns.
Y’all may have noticed that I mentioned no DA revolvers. Well, I had realized, by late last year, that pulling long-stroke double-action triggers was something that my right index finger should not keep doing. Just last month, it started becoming apparent that my left index finger was becoming similarly afflicted. I plan to maintain overall hand strength, but, should not concentrate wear and tear on my index fingers. If one is going to be cocking a hammer, it might as well be a more-ergonomic hammer, as found on single-action revolvers. As long as my accuracy remains decent, I will keep using my much-loved DA revolvers, but my dry-fire practice routine is suspended, indefinitely, and I will no longer be doing much double-action live fire. For this thought exercise, I selected a good utility rimfire SA sixgun, and a high-end centerfire SA sixgun.
The 1911 pistol was my first love, among handguns. As long as I can still run a slide, I plan to keep using the 1911 system. Steel damps recoil. The low bore axis, and the gently-accelerating .45 ACP cartridge further contribute to mitigation of muzzle flip.
The Glock 17 is a wonderfully “orthopedic” pistol, for aging hands. Gen4 fits my hands better than previous versions. I bought my first Gen4 in September of October of 2015, shortly after my then-chief OK’ed 9mm to be an alternative duty cartridge, and it remained one of my duty pistols until I retired in 2018. (I transitioned from a .40 SIG P229, a weapon with harsher muzzle flip.)
I mentioned no compact handguns. That was intentional. It has been some time since I liked shooting any of them. I can live without them. So, when the thought exercise limits me to just a few choices, no compact handgun will make the cut.