Interlock? Or SST?

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I think your .308 is fine for Elk, I would as said before just load up a 165 Nosler Accubond, just because those partitions do so well on controlled expansion aiding in penetration.

I don't have much use for magnums though, so I'm showing my bias. With today's bullet technology, it has really improved performance.
 
Bullets are designed to work within a certain velocity range. Most bullets will expand AND stay together between about 1800-2800 fps. If they impact faster than 2800 fps they tend to come apart and not give adequate penetration. Slower than 1800 fps and they act like FMJ and don't expand. Those speeds aren't carved in stone, there is a lot of variance between manufacturers and different bullets. Many premium bullets will stay together at impact speeds well above 3000 fps and some designed for 30-30 class cartridges will still expand at speeds below 1800 fps. Others need at least 2000 fps to expand.

Any 150 fired from a 300 mag is going to start out well over 3000 fps and could fail at closer ranges. On a whitetail they may make a mess of the animal but will usually still kill it. On a bigger animal you may have lots of damage for a few inches, but the bullet may never reach vitals. Especially if shot from a less than perfect angle.

If you're going to shoot 150's on a big animal you need to be using tougher bullets. The SST's in particular are noted as a softer bullet that expands well at slower speeds, but doesn't stay together well at faster impact speeds. The interlock is a little tougher bullet, but I'd shoot a heavier bullet at slower speeds. If I were sold on 150's I'd look at Nosler Partitions, Accubonds, or try the all copper bullets like those from Barnes. Those have a reputation for staying together and giving good penetration. Hornady makes a good bullet, but you need a heavier bullet at slower speeds. A 180 SST would probably work.

Interestingly the 150's would actually be a much better choice from a 308 than a 300 WM. They leave the muzzle at about 2800 fps from most rifles and don't fall below 1800 fps until they are beyond 500 yards.
 
There are managed recoil loads available for the 300 WM as well. Remington has a 150gr @2750 or so (which pretty much mimics a 308).
 
@jmr40 great explanation on something that most beginners don't realize with bullet technology. I always limit my range in accordance to impact velocity as it relates to adequate expansion on the projectile, and keep in mind that some projectiles have thinner jackets for lower velocities.
 
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I’d use the Interlocks between the two. The 150’s kill elk from a 30-06, I’ve done it lots of times. The 150 Interlock comes apart pretty easy at 30-06 speeds, probably will even more so from the Win Mag for reasons already posted. Therefore I’d try to shoot lungs or neck with that load and try to avoid the shoulder. It will get the job done.

I bet I’ve personally seen over twenty elk die to the 150gr Hornady Interlock. I’ve cut up even more than that. We used it in the family for years. Mostly cows, couple small bulls. That must sound like an endorsement but I’ll never, ever go back to that load having seen how other loads perform from the 30-06. It’s a capable offering but it’s far from optimal.

If you aren’t worried about your marksmanship and are comfortable with that load and don’t want to mess with changing it, my advice is to have at it. Go hunt and have fun. It’ll do. But If you are worried about shooting a GOOD elk bullet from a 300WM, my advice is to go up in bullet weight and/or shoot either a partition, a bonded bullet, or a monolithic copper bullet.

Post pics of the hunt when you get back:)
 
I just want to add, will a 150gr bullet from a .308 work? Probably but on a hunt is it really a good idea?

You shouldn't use a cartridge that will do the job when everything goes right, you need a cartridge that will do the job when everything goes wrong. Prepare for the worst case scenario and enjoy your hunt when everything goes the way you planned.

Not my words, they came from my grandfather when I was growing up. (paraphrased)
 
SST’s are very similarly constructed to Interlocks, but with a non-deforming polymer tip instead of a soft lead tip. Both are non-bonded cup and core designs with an “inter-lock” ring inside the jacket, both spitzers - but when an Interlock runs into something, its soft lead nose deforms ever so slightly, retarding the initial expansion. The SST, alternatively, has a hard polymer tip which remains rigid, instantly initiating expansion upon contact, driving itself back into the bullet core. So one is a charcoal grill, one is a charcoal grill with match-light charcoal - just a little easier to get started.

That difference can be enough to create a dramatic difference on how they perform on game. I wouldn’t necessarily say the Interlock is good for any game for which the SST is not, but impact velocity and range might sway my decision between the two.

Given the context of elk hunting with a 300win mag, neither bullet would be my choice for elk, and neither bullet would be my choice for 300win mag. If I’m elk hunting, it means I’m out of state, with limited time and opportunity to hunt, and probably a lot of money wrapped up into the hunt/tags/travel, so I’m not taking any chances. The 300win mag is too much horsepower for either of these bullet designs at short ranges without risk of bullet failure (excessive weight loss, jacket & core separation). Just not a chance I take.
 
I run 150 grain SST in my 308 for Whitetail hunting and it's a great Bullet For That. Jmr already explained this a little bit but let me give you a real world situation that occur with me just this last weekend. I had the 150 grain SST leaving the barrel at 2950 FPS. Ended up with a broadside shot at 30 yards, slipped the bullet and right behind the shoulder with a nice double long shot just like I would with a bow. At the shot, dear did a high rear leg kick and ran 50 yards and fell over dead fortunately I saw it fall as there was no exit wound and absolutely zero blood around the entrance hole. The impact velocities were just too high and the bullet over expanded didn't penetrate through the deer. Had this been in thick cover or I couldn't see the deer fall, it's very likely would have been a lost animal. The point being in a 300 Win Mag you're going to be pushing that bullet even faster so unless the shots far enough away for it to slow down considerably before impact, especially with a Target that provides much more resistance than a whitetail, you run the risk of the same thing occurring. So if you do decide to run 150 grain SST, please be very careful that you don't shoot one at very close range with those High velocities. You would be much better served to either choose a heavier and/or tougher bullet. That bullet is just not suited that well for the target and the caliber you are planning to use. The exception to that would be if you are expecting your shot to be 300 yards or more. But you still would have to be very careful with close range shots as it would likely under penetrate Andover expand especially at 300 Win Mag velocity
 
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