Note the disclaimer, "Were I you", I gave my preference in .257 bullets for hogs based on what I've used successfully in the past, the best being the Nosler Partition.
If you prefer the Hornady Interlock, by all means use it!
I do think that if you did a survey among experienced hunters asking which medium game bullet design was the most reliable under a variety of conditions, the Partition would be ranked considerably higher up on the list than the Interlock (this is assuming that the Interlock would even make the list).
In fact, I'd be willing to bet that if you asked a Hornady Tech Rep about the best .257 diameter bullet to use for game that might go 600 pounds and require shots from the rear quarter, even THEY wouldn't recommend the interlock, they'd probably steer you toward their more reliable ,deeper penetrating, "Premium" InterBond or GMX bullets!