Yes, I will, and I will because it is the MAIN problem that novices in science and physics (no offense meant) face, and that is that, while they know what CAN affect something, they know not to what DEGREE it will affect it. The concept of significance is just utterly lost.
Sure, there's certainly some affect that the presence of air will have on the bullet in the barrel that wouldn't be there in a vacuum, but it is so very little that it would be hard to measure.
Atmospheric air is 14.7 psi. That's 14.7 psi air pressure in the barrel vs 60,000 psi of a decently loaded .308 behind the bullet. Now, remove the 14.7 psi of atmosphere, and you increased the pressure difference by 0.025% Your chamber pressure, on the other hand, won't change.
As for your comments about water....no. It has to do with density. Water is approximately some 775 times more dense than atmospheric air, so whatever you fire in it is going to have serious issues dealing with it. You cannot, in any meaningful way, draw any sort of analogy between shooting in water vs atmosphere, and atmosphere vs vacuum.
It's like saying, because I punch really slow underwater, I ought to be able to punch at LIGHTSPEED IN A VACUUM!!!! ::::insert mad air, er, VACUUM guitar solo:::: when there is statistically no difference between vacuum and atmosphere when comparing it to air and water.
I'm very much aware that sometimes experiments don't go correctly, but dismissing the statistically irrelevant usually is not problem; rather, it has to do with the statistically relevant. In other words, the caliber you choose will have thousands more times the effect of the sudden lack of atmosphere.
If that didn't compute, I must recommend remedial physics classes, sorry.
Chuck, good point, but it's actually the same thing. A force back towards the shooter acting on a moment arm going straight up from his shoulder does the exact same effect as a vertical force acting on the moment arm going straight out from his shoulder. It's like one of those multi handled lug wrenches...lifting UP on the right one does the same thing as pushing LEFT on the vertical one.