Sure, I did it. I started with a Fanner 50. I have done it with other guns over the years, after carefully checking their loaded condition (violation of rules #1,2,3).
After reading the book: Fast and Fancy Revolver Shooting by Ed McGivern, I bought one of those Italian SAA clones, bought a fancy holster in Tijunana, loaded up a bunch of .45 Colt cases with wax bullets and spent about 10 minutes learning to become an exhibition shooter. I realized it was silly and dangerous and gave it up. I also got too fat to put on the gun belt.