There are so many factors to consider. However, you are asking all the right questions. Does she want all steel? How about size of grip? Indeed, size has always mattered. Finish is always an issue since blue finishes can take a beating in women's luggage, er, purses. Do you want SA or DA? Is magazine/cylinder capacity a concern for her? Budget? We can never forget budget. Ease of cleaning? Will she ever target practice with it? Those all seem important questions to answer before making recommendations.
Why you might ask? The other day, while riding in the car with my lady friend, the matter of firearms came up and she made her wish known, "I want a pistol for my purse. Something small [gesturing with both hands maybe three inches apart]...like a .45." I turned to her in surprise. "What? What? Why are you looking at me like that," she said in response. I got the car back into my own lane.
You can never know what women really want (until you ask, write it down, and/or record it just to make sure)...
...Oh, by the way, don't you think it's coincidental that your female co-worker would just happen to consult YOU about a gun?