The rifle you're shooting makes no difference. You will still need to FL resize every time and watch case lengths and OAL. You get to use pointy bullets though.
If you don't have brass, you have a wee problem. Winchester only makes brass and ammo, periodically.
However, I've always found at least starting with the powder given for the accuracy load in your manual is a good idea.
Slow moving bullets kill the same way any bullet does. Shock.