Suicides are another issue. I've been on scenes in which an attempt has failed, using a centerfire cartridge. Here, when we discuss caliber size and power, it's usually in a defensive concept. While a few of us still can't get past the concept that any defensive fire should immediately kill an attacker and obliterate his remains beyond recognition, most understand that merely ending the threat is the most prudent goal.
I still think that most of us living a "safe" lifestyle (not out looking for trouble the way cops are required to do) could live ten lifetimes and not meet anyone who would continue an attack when faced with a well-executed rimfire defense. I bet if the individual whose skull appears in the images above had received those wounds as the result of such a defense instead of self-inflicting them, he still would have promptly stopped whatever he was doing that got him shot in the first place.