Yup, muzzle up, cylinder open, I like to put my strong them on the hammer spur (if it's got on) to make sure it's clear of the brass. Hit the ejector hard, bottom it out, and that brass will go a flyin!
It really is absolutely not an issue with a quality revolver. I have NEVER had it happen while shooting or during reload drills. IMHO, one is more likely to get a bound revolver from a bend moon clip than one is to get a rim under the star when not using mooners.