Bill B.,
Happy to oblige. If your mind is set on an DA revolver with adjustible sights, I'd have to say the S&W's are going to be the hands down winners. If you are willing to go the extra $150 to $200 (even for something like a used classic S&W K-22) to get what you want, you'll be money ahead down the road.
It's my personal opinion that when it comes to .22's, you should buy the best quality you can afford. Why? .22 ammo is so inexpensive, and the round is so much fun to shoot - that you will be running literally thousands of rounds through it. And faster than you may think. I never go to the range with my .22's where I don't go through at least 300+ rounds. Whereas you can do that with .22's for under $10 - even the least expensive factory loaded center fire 9MM's & .38's are going to run you at least 4 times more. When you are cycling rounds by the thousands rather than the hundreds, little imperfections (sights, grips, triggers, extraction, mis-fires, broken or pre-maturely worn parts, etc.) get real irritating real fast.
If you are more interested in target shooting than the mechanics of the particular handgun - might I suggest a .22 semi auto pistol or a single action (cowboy type) revolver. I of course am a Ruger fan, and that company makes the most popular .22 auto out there (the Mark II and new Mark III's). Most varients of these are going to be much less expensive than comparable DA revolvers. They are practically indestructable, and the basic design has been around for more than 50 years - with after market parts and accessories available for them second only to the Colt 1911 design. Ruger also offers several single action revolvers in .22 that tend to be less costly than comparable DA revolvers. Again, long term proven designs with plenty after market parts and accessories available. Some of those models can also be had with interchangable .22 LR and .22 Magnum cylinders (if you have a need or desire for something with a bit more punch to it). But above all, go with quality makers like S&W, Ruger, Browning & Beretta.