I like all of them
4506, 4567, 4566, 4563, 4516 (I bought the first one when they first came out; have owned two -2's since; prefer them to -1 style), 457; My experience is they are all dead solid reliable; never had a glitch.
I didn't shoot so well with the 4567 and CS45, but never had a malf, either.
My 4506's have been police trades; one had apparently been worked on for a marksmanship team.
Main negative; they're heavy; but they're built like tanks; they grow on you.
Currently own 4506, that works with 4516 slide, CQB (Performance Center 4563) & 4516-2. Will buy another 4563 and another 457, if a good deal on a 4506 or 4516 comes up when I have cash I'll snarf them up. Have owned several 457's. People keep talking me out of them, or I give them as gifts to friends just starting out.
I want an old style 4513. Never owned one. Also have owned several 69 series 9's. Liked them too.
I think they're terribly underrated; deserves a second look and upgrade at S&W sales dept. Can't tell the difference in feel between 4563 and Sig 220.
Cheers, TF