Funny how the city folks want to "just leave the poor snakes alone.". That's easy to say until you live every single day watching for the damned things. I was bit by a copperhead in my front yard several years ago when I lived in East Texas,(It was dark..I couldn't see it) and more recently I had a fine Border Collie killed by a rattlesnake. Since moving out here where I live now I've killed about 12 rattlesnakes.
So, my rule of thumb is this: if it's within a couple of miles of my home and family, I do everything in my power to kill it with whatever's handy. If, however, I come across one while hunting out and about, I let it go.
Also, FYI, I've tried the 22 LR shotshells and found them seriously lacking. I keep a 3" 38 Spec. with handloaded shotshells. It's devastating. Ditto for the 9mm and the Speer shotshells.
The above applies ONLY to poisonous snakes. I give the non-poisonous ones free reign, and go out of my way to leave them be.
35W