I too have lived all my life in copperhead, cottonmouth and rattler country. Never had a situation, nor can I imagine one short of a sci-fi movie, where I had to kill one.
Most snake bites happen because the person wasn't paying attention and stepped on (or nearly) the snake or was stupid enough to try and handle it. They will try to escape if they can, if they sit still they are either afraid you will eat them if hey don't keep an eye on you, or too cold to move.
Keep junk and brush piles away from the house, keep rodents, frogs etc away from the house and keep your eyes open. Anyone hiking on a trail should know enough to watch their step.