all my knives get handled , I dont worry about finger prints , they get wiped off after use , well sometime before the end of the day anyways. I have one knife that drives me nuts trying to keep the blade print free and that is a lil Case whittler , where the blade is polished. Usually I don't worry about it , if others handle my blades and get prints , smears or smudges on it , so be it , i buy mine to use , not to look at . For some who collect then I can see worrying about the blade and prints , oils , sweats , etc. I have seen some friends who carry S30v bladed folders and the blades develop rust from their sweat so yes it can happen, usually over time.
Wipe em down occasionally if you use em , if you collect em be prepared to wipe em down often if handled alot.