Where those would work exeptionally well would be at longer distances on small woodchuck/prairie-dog size critters, where a bit less velocity will not hamper the bullet's design to open up well when hitting the beast.
In other words, long shots are going to be effective - even when the bullet may be moving anywhere from 25% to possibly 35% slower than the muzzle velocity.
I wouldn't use a bullet that is too frangible on impact when shooting larger animals like coyotes as they tend to take a chunk out of the flesh that is a lot more like a major surface wound. I have taken a few coyotes at fairly close range using 50g Speer TNT's moving right along at 3,995 FPS from my 22-250 over a chronograph. I have never had a bullet just fly apart and have shot this load combination over 500 times (even though they state that the bullet may fly apart from centrifugal force if driven beyond a certain speed). I guess this is one of those "other user's mileage may vary" scenarios - where mine certainly seem to vary - from what would seem to be the 'norm' - as for bullets not reaching their intended targets.
This is maximum load using IMR 4064 (blue label) powder with BR2 Primers - which the gun LOVES. I can shoot off a bench and pull a 1/4" group at 200 yards! That is correct - .25" group (smaller than a dime) at 200 (two hundred) yards. I mentioned this once before and got drilled like I was lying or something. Nope, that is the TRUTH - like it or not!
A shot directly behind the right leg into the right chest wall (through ribs) at 40 feet away and the coyote turned to run away from me, and sort of slowly limped - hopping about 50' around and away in a semi-circle, from me before fully collapsing and not moving one bit once it hit the ground. The bullet essentially made a 4" diameter opening large enough for me to place a clenched fist just where his heart would have been before the shot - in other words, a 4" diameter crater that was about 4" deep.
It appeared that his heart had been literally removed out through the large crater along with the blast of the bullet's shrapnel essentially making a full 180 degree turn - from going inwardly to going outwardly. If you have ever shot a thick steel plate with a fast-moving bullet and observe the crater where the blast is actually directed 180 degrees backwardly, that seems to be what happens when the "exploding" projectile at those speeds hits meat.