According to Chuck Hawks...
According to an e-mail from Dudley McGarity, the Apex is safe for use with mid-level .45-70 +P loads of the type suitable for Marlin lever action rifles. These are usually defined as not exceeding 40,000 CUP MAP. (Note: It is not intended for use with the top level of .45-70 loads, which generate MAP's in the 50,000 CUP range and are for use in single shot Ruger No. 1 and Browning/Winchester High Wall falling block rifles ONLY.) However, in our experience, SAAMI standardized loads are entirely sufficient in the .45-70 and +P loads are simply not necessary.