i love rimfire revolvers, but got rid of a ruger lcr 22wmr and replaced it with a ruger lcr 22lr for a sometimes ccw. 22wmr out of a short barrel was way too much flashbang for too little result, even with handgun specific ammo. i was unable to keep shots on target. the lcr 22lr is superb.
i also like an airweight s&w 642 38sp snubbie for a ccw, but only shooting softer wadcutters.
of these two, i get much more (necessary) practice with the lcr 22lr, and 8 consistently accurate center mass 22lr hits would likely serve my humble suburban needs. if i were to be in the outdoors awhile a ruger single six loaded with 22wmr, and packing the 22lr cylinder, would be my choice.