I rarely carry anymore, because where I work doesn't allow carry and I don't venture out very often after work, preferring to come home and do stuff here.
So, for my work-day EDC, I have narrowed it down to a Case Trapper, a can of chew, my Blackberry, my iPod Touch and my wallet and keys. At work, everything but the Trapper goes into my desk drawer.
Outside of work, I still carry my phone, wallet, keys and chew, and while I occasionally carry the Trapper, I usually carry either my Griptilian or my Endura. I don't get any hassle at work over the big knives, but the Trapper is just more practical for me at work than the other two.
If I do pack a roscoe, it is going to be my trusty ol' Taurus 605. I had a Kel-Tec P3AT that I liked for certain things, but the buddy that gave it to me moved back, so I gave it back to him. Probably I will buy another or something similar to replace it.