Energy on target is much over emphasized when judging the performance on game. In my opinion, there are several factors that are more important. My own order of precedence is:
Bullet placement
Bullet Construction
Bullet Sectional density
Velocity at point of impact
Bullet momentum (mass * velocity)
Efficiency of bullet energy transfer to target
Total bullet energy available for transfer
While a number of these factors are related (and I don't want to get into the math here), the first point is that the bullet has to get to the right place on a target and then it has to punch a hole all the way into the vital area and do so while causing enough damage to ensure a humane kill. Higher velocities may allow a bit more margin for error, but so do high sectional densities.
But the bullet has to be the right one for the job. Quibbling over a few hundred (or, past a certain point a thousand) foot pounds of energy is just quibbling. Ballistics tables are an aide for sighting in the rifle, but do not provide anything other that a superficial indicator of how the bullet will perform on game. Other things are far more important.
And, my own rule of thumb is that you get 10 more yards of effective point blank range for each 100 fps of velocity.
The three cartridges named, 270, 6.5 Swede, and 7-08, are in my mind equivalent for the hunting I do. If I had to select only one for medium game (thank goodness that I don't), I would probably take the 7-08. My 7-08 is a light, handy tack driver (Remington Model 7 with 18.5" barrel, fiberglass/kevlar stock that weighs a bit over 6 lbs.) that is light enough to carry all day.
It is the overall system (rifle, bullet, and shooter) that matters. FPE is of only middling importance.
In my opinion.