A few bouncebacks from shooting .22s and .38s at old tires. I was a slow learner. I don't know about an inflated tire, but even the sidewall of an unmounted tire is pretty resistant to low-power, round nose bullets... lots of flex there to absorb energy, even though it's just mesh and rubber there.
I did get shot in the head with a .44 Magnum Desert Eagle, though.
A friend and I were shooting his DE at the old airport range in Memphis. We'd had a couple of my reloads that failed to fire. Jay shucked them out and continued shooting. When it happened to me, I laid the gun on the bench pointing downrange. I had seen "dud" rounds go off suddenly with other shooters; I didn't want it to happen while I was working the slide, even if nothing had happened when Jay cleared the gun. So I stood there while I counted 60 seconds by my watch. The second time, I laid it on the bench pointed downrange and bent over to pick up some empty brass while I was waiting. As I was straightening up, BOOM! Knocked me down and I saw stars and tweety birds, just like in the cartoons...
Jay had gotten impatient and picked up the gun. I don't know if it was just when the round decided to go off, or if it was the jostling that did it. Fortunately it was still pointing more or less downrange when it went off. Mass time velocity, and all that... 240 grains went one way, and 30,000 grains of gun went the other. The gun wasn't moving nearly as fast as the bullet, thankfully. A loaded Desert Eagle weighs well over four pounds, and it had about a two foot running start when it raised a big knot on the side of my head.
In retrospect it might have been a bad idea to keep shooting after three duds, but I'd had occasional duds from factory ammo, and maybe one out of five on cheap .22LR. I did eventually figure out that the problem was a bad batch of primers, and I wound up throwing away most of a brick of Large Pistol Magnum primers.