For the early part of my shooting life, I bought the cheapest .22 ammo I could find because that's what I could afford. I never remember having problems with misfires out of my old single shots, and accuracy was measured by knocking cans over.
Later on, I learned about trying to get the best potential for accuracy (affordably) with better rifles/scopes etc, and finding the ammo they liked. So trying different brands, weights, velocities in semi autos, I've seen a lot more misfires. Some of the cheap newer Winchester stuff is crap, as is a lot of the Remington. I've had less issues with Federal or CCI than any and had a few with some Aguila SE.
I gave my cousin 10 rounds of Eley Tenex to shoot in his new 10-22 build. He'd just fired 50 rounds of mini-mags without a failure, but only managed to ignite 4 of the Tenex rounds. I loaded the same "duds" in my 513T and shot them all in the same hole.