Jeepnik, are you refering to one handed revolver manipulation? If so, would you mind outlining the process? I'm having a hard time visualizing how one would go about reloading a revolver using only one hand.
A few years ago, my brother broke both the bones in his dominant (left) arm just short of the wrist, and we did some research and practicing of one-handed firearm manipulation as a result.
Here is what I worked out for administrative handling of the revolver one-handed (for someone with hands my size-- large gloves):
With a J-frame .38, if you are using your right hand, the cylinder release is still activated by the right thumb, and then the cylinder is popped open by the trigger finger or a combination of the trigger and middle fingers. Then you shift hand forward, cupping the revolver so that the trigger finder is around the frame under the barrel, the tip of the middle finger gets the ejector rod, the thumb curls over the top of the frame, and the ring and pinky finders curl around the front of the grip frame or the trigger guard, depending on how things fall out for you.
The middle finger actuates the ejector rod. If you are just unloading your gun, they should fall out with gravity, but if you are reloading a gun you have fired dry, on a J-frame with just a fingertip on the ejector rod, in what is probably an awkward manipulation, the empties may not all come out, or not all come out all the way.
That's okay, because the next step is to lay the gun down anyway, with the open cylinder up. Lay it down on your thigh, you shoe, your opposite forearm, a table, a chair, the ground, whatever the circumstances dictate. I've read where someone thought you could stuff the gun down inside your waistband with the ejector rod hooked over your belt, but I've never been able to satisfactorily get that to work, even with a K-frame and a 3 or 4 inch barrel. It'll go in and stay there, but I don't like it. With my little 642, it's never going to work because there isn't enough barrel length to hold it in place, like there might be if your belly and belt work to do that with a longer barreled, heavier gun.
So, for me, the gun is laid down on something or some convenient body part. If the empty cases didn't come out all the way when you did the ejector rod thing, pluck them out individually now.
Access your reload. If they are loose rounds, put the rounds in one at a time and slide them in all the way to the rim. You can turn the cylinder to give you better access to the empty chamber you are trying to load if you need to. If the reload is in a speed strip, do one or two at a time, but make sure that after you strip them into the chambers, you push the rounds all the way in. Once you have finished filling the chambers, hook your thumb around the cylinder, your fingers on the far side of the gun, and push the cylinder back into the window and lock it in place. Pick the gun up and shift it in your grip until you have it back in a shooting position.
If your reload is in a speed loader, you won't be able to put your rounds in while the gun is lying down. You will have to try the belt thing so that the rounds can fall into the chambers. For myself, I fumble speed loaders enough when I have both hands. If I'm one handed, I hope I'm not down to just my speed loaders to reload my revolver, but if I am, I'll dump them out of the speed loader and use them loose in preference to trying to line everything up at once with just the one hand.
Experimenting for yourself is the way to work this out. Please use dummy rounds! Also, to ensure that you are truly doing it one-handed when you practice, if you have the use of both of your hands and you are doing this for future reference, put a sock over the hand you don't intend to use to remind you not to touch the gun with it.
Opening the cylinder left-handed is tricky. I flip the gun around in my hand so that the trigger guard is against my palm, so that I can hook the cylinder release upward with my left thumb and pop the cylinder out with the tip of the middle finger. Holding the cylinder open with the left thumb, the left trigger finger pushes down on the ejector rod while the middle finger is hooked through the frame window. The cases don't usually come out all the way, but can be removed and the revolver reloaded as above. When you close the cylinder, press it into the frame with the tips of the trigger and middle finger, while the thumb is on the opposite side of the frame and the ring and pinky fingers are curled around the grip. Then adjust to firing position for continued action or reholstering.
This process is not fast.