The original M16's had a 1:12 twist which helped the 55gr FMJ yaw for best terminal ballistics. Most modern rifling has a much faster twist and may not create the yaw need for tissue disruption.
http://www.dtic.mil/ndia/2008Intl/Roberts.pdf
about half way down this page has some good rifle terminal ballistics:http://www.ar15.com/ammo/project/Self_Defense_Ammo_FAQ/index.htm
link to Dr. Roberts' forum: http://pistol-forum.com/forumdisplay.php?19-Ammunition&
edit: Spelling and grammar.
http://www.dtic.mil/ndia/2008Intl/Roberts.pdf
about half way down this page has some good rifle terminal ballistics:http://www.ar15.com/ammo/project/Self_Defense_Ammo_FAQ/index.htm
link to Dr. Roberts' forum: http://pistol-forum.com/forumdisplay.php?19-Ammunition&
edit: Spelling and grammar.