I find 2400 to be a good powder to have on hand. You can load it in 30-30 to .44 Magnum. In my .44 Magnum @ 20.5 grains with a 240 grain XTP it will leave some unburnt grains, but it is very accurate, and it does pack a punch with a nice flame.
For lead bullets I don't think you can beat IMR 4227 up around 22 grains. It gives you around 1300 to 1350 from my 5.5" Ruger SA, and is very, very accurate. It also shoots to the POA of the 2400 load.
I have loaded some True Blue, but I am a little worried about flame cutting with the small ball powder, but it is very accurate with lead bullets, and is pushing 1250 fps which is no slouch with a hard cast LSWC or a large meplate FP bullet.
The .44 magnum is so versitle with in its loading that you could use just about any powder and find something that will work. There is a reason they say, "you can load it from mild to WILD!" Just talking about it makes me want to grab a 100 round box, and to shoot some 2 liter bottles filed with water, and then ring the spinners I have.
I have to admit though that the 1911 has taken the place of the .44 Magnum for fun blasting, and the 9mm hardly gets shot, but the 9mm to me is like my BB gun I have had since I was 7 years old. I never aim it. I can point shoot it more accurately thab I can trying to use the sights.
Grab you a # of IMR 4227 for lead bullets, and a # of 2400 for jacketed bullets and get to loading. If those don't work out then you can jump to the more finicky powders like W296 and H110.
Despite others success with Unique, and my own success with it in 9mm. I could never get it to shoot well in my .44 Magnums. YMMV.
For super light 800 to 900 fps and for newbies who want to say they have shot a .44 Magnum I call on Trail Boss. It is dirty, but what isn't that gets set on fire or explodes? Think about it.