You could have the chambers in a Ruger .45 ACP cylinder recessed, after which you could fire both .45 ACP and .45 Auto Rim cartridges. However I see no reason to do so. The purpose of the Auto Rim round was so one didn't have to use 1/2 moon clips in a hand ejector, and single action style revolvers don't use clips in the first place. This seems to be a answer looking for a question.
I think you can more easily get uniform headspacing of the Autorim by trimming the Ruger .45 ACP cylinder on a lathe, rather than drilling or milling individual recesses for each rim. Just a thought.
I have several reasons to convert the Ruger to Autorim: compatibility with the ammo I use most frequently in my S&W .45 ACP/AR revos; because I feel my Rugers cycle more smoothly with Autorim cases than they do with ACP cases; and because the Ruger is more sensitive to case .45 ACP length and headspacing than a 1911 or even a S&W 625, and .45 ACP case length, in my experience, varies all over the lot. Short cases that work fine in a 1911 due to the extreme firing pin protrusion available on the 1911 may not fire in the Ruger with much more limited firing pin protrusion.