Poor Grips - Get the get the Black Widow, it also has the bigger frame, two inch barrel, and enhanced sights.
Single Action - ? Guess that is preference.
Slow to re-load - Yep, but how many rounds do you need in a pocket pistol. If you feel the threat is sufficient, carry bigger and more. The "what-ifers" will always argue you can get into a gunfight with a dozen, 360LB, meth-crazed, gangbangers at your local Sonic Drive In over the junior Cheeseburgers. So in that case its slow.
Poor Choice of rounds- There is always better. A .223 is better than a .45 and so forth. Again, what do you feel comfortable with. I grew up on a farm in the 60s, when just about everyone I knew had a .22 pistol or rifle in their truck. We shot squirrels and rabbits, killed skunks and raccoons in the garden, coyotes in the chicken pen, and put a lot of beef and pork in the freezer. If it was hunting season and you drove to high school, the gun was in your truck
. You might even bring it to Agriculture class for show and tell
. And when I went to college, ROTC had a marksmanship team.
I don't have an issue with a .22 in my pocket most places I go. I do own larger calibers and carry them when the occasion and activities warrant. But, I never count the lowly .22 as ineffective. It's been in production for 127 years for more than one reason.