I just went through this myself, and after lots of research I really liked the following:
S&W Model 34 (1970's model I think)
I like this gun because it is built on the J-Frame, versus the K-Frame that the Model 17 and Model 617 are built on. The smaller J-Frame is plenty big for a .22 and points and shoots a lot better IMO. The only downside to the Model 34 for me was the fact it was made out of steel and could rust, this led me to the
Model 63. The 63 is basically a stainless steel version of the Model 34. I do not like the new S&W aluminium .22's.
I also like the new
Ruger SP101 for the same reasons I like the S&W Model 63. I found the S&W Model 63 a littler easier to shoot accurately, although I'm not sure why. In my tests the Ruger seemed to stay cleaner for some reason and I eventually had a couple cases get stuck in the S&W 63, but they were not that hard to get out.
I also looked at a
US Fire Arms 12/.22, and thought it was one of the nicest built guns I looked at. Several guys at the indoor range I go to have these and love them. This is a single action gun. Although I think this gun was way better built (finished) than either the S&W or the Ruger, I couldn't fire it well no matter hard I tried. One of the guys at the range had his worked over by a company called Long Hunter in Texas. I was able to fire this one much better, but still not as good as the Model 63, or even the Ruger.
Finally, I looked at a
Freedom Arms Model 97 with a 4.25" barrel. This gun was absolutely amazing! Everything was perfect and the gun fired like a laser! I think it was single action, but don't remember. The gun I used cost over $2,000 new so it is obviously in a different class than the other guns. I doubt you could find a more accurate .22 anywhere!
I ended up with the S&W Model 63 and have been very, very happy with it. It rides in the side pouch of my backpack or on my hip everyday when I'm in the mountains or at my cabin. It is fun to shoot and almost as accurate as the Freedom Arms, but was much, much cheaper. It has put plenty of meat in the crock-pot over the last year.