The gel tests are not so impressive. Low-velocity, lightweight pistol bullets do not perform well in hollowpoint design. This is not just a .380 problem. Even 9mm HPs don't reliably expand, so it is not surprising that .380 doesn't expand so well. They frequently peel open or deform quickly before getting good penetration. Humans are not gel blocks. There are buttons, zippers, fabrics and seams, leather goods, stuff in pockets, not to mention bone when shooting for the boiler room. We are shooting for the boiler room, aren't we? Even eliminating bone and non-bone factors, humans are not composed of a uniformly viscous substance like gel, and there is little muscle fiber in gel. Thus 6" in gel and 6" in muscled-out BG wearing a heavy field jacket like the Terminator are not the same thing at all.
Many times HPs simply do not expand in such slow cartridges; they either deform or act like a solid. If the HP hole is plugged - with fabric, etc. - the bullet very may not expand, in which case it will function like a FMJ. But you can't count on that - you may get explosive fragmentation as the round enters the body or pierces fabric, etc.
I've been shooting .380s since teenagerhood, and feel comfortable using it for SD. But I would not use a hollow point. I've shot many thousands of rounds at all kinds of things out in the sticks. The FMJ is a pretty destructive round in .380 and can penetrate surprisingly well. I would shoot things like an old, unused metal pressure tank that came off a water well (tank empty, of course). The FMJ would punch through the tank every time. Sometimes the HP would, often not. Several times it dented the far wall where it hit, but sometimes there was no far-wall dent. Good ammo, too, not 50 years old.
Do yourself a favor - FMJ.