.
I think that as long as you are comfortable with a revolver and can
shoot it well, the .357 Magnum caliber in a medium/large frame would suit
your purposes better than a .45 ACP caliber pistol.
For HD and showing off (range), a .357 Magnum through a 4" barrel will be
at least equal to the .45 ACP, and will likely outperform in terms of
accuracy.
As others have mentioned, the revolver and its ammo (.38 & .357) might be
less expensive, if that is a consideration.
It is important to remember that there is no wrong choice here. This is a
personal preference issue.
Will anyone else in the house be using the gun? If so, maybe their
preference should decide.