The laws of physics are helpful here, inasmuch as we can say that a BB fired at 400 fps will carry more destructive power than a brick at 10. The collective sense of owners, as captured by reports and surveys, is that .38 spl or 9mm represent the lower end and .45 and .357 the upper of a standard CCW round. Go lower and stopping power requires precise placement with no room for error, and higher leads to rounds that are difficult to control and weapons too large to comfortably conceal.
Outliers abound, with many reports of smaller and larger calibers proving successful. The calculus is dynamic because smaller rounds allow for better concealment or more rounds carried, larger rounds have more force but less capacity onboard. I've found it easy to put all 6 or 7 .357s in a tight group, but can't manage that with a .45. For me, a .357 is comfortable, whereas the .45 is just too much gun. Others handle the .45 with aplomb. So...
That's about all you can say.