Ala Dan, I've got a box of Super Vel...
It's yellow, and says POLICE ONLY, 110gr JHP .357 Magnum. I guess it was pretty spicy stuff for it's day, but my 158gr .357 Magnum Desert Eagle handloads would probably eat it for lunch now.
I trust my handloading skills, but carry factory ammo for defense. Between the criminal and (sadly inevitable) civil courts, why give the opposition any chance to make you suffer for what should be a clear-cut case of self-defense?
Mtnbkr, trust me, I toured an ATF crime lab when they offered to hire me away from my Air Force forensic lab job back in 1998. The ATF had deep pockets after the Oklahoma City bombing, and their lab showed it. I collect odd ammo, guns, and reloading tools/components. My collection pales in comparison to the reference standards they showed me that day. I struck up a conversation with one of the technicians, he had RCBS and Hornady reloading presses set up right there, and an astounding selection of components to assemble duplicates of anything they found out on the street. Then there's the various chromatographs, x-ray diffractometers, scanning electron microscopes, optical stereomicroscope comparators, and chemical analysis techniques like thin-layer chromatography. All stuff I was used to in the Air Force lab. I was more in awe of the reference standards, and mentioned how jealous I was, because I usually could only afford a pound or two of IMR4895 at a time. It turns out that he was a reloader at home, too, and agreed with me. I was thinking to myself that if I got hired there, maybe I could use their lab setup to make some serious match-grade ammo after hours.
This ATF forensic lab (rather well hidden, I might add) was in California where I had been stationed for 10 years. I let the Air Force bribe me into taking an assignment in Florida, so I snubbed the ATF offer and am finishing up my 20 years active-duty time before I go look for a post-retirement McJob.
So yes, they do know what to look for when it comes to evidence, and I have no doubt that state and local crime labs have those capabilities, too.