Enjoyed reading all the above threads.... then thought about my own situation where you might encounter a python when you least expect it.. Since I work in Everglades National Park (and they aren't exactly gun friendly) that leaves me with few choices.
A panga or machete, or..... If I have a chance I'll kill everyone I encounter (and that's what the rangers there are supposed to do as well - since they're absolutely changing the eco-system by eating every small animal they encounter). I've considered a .410 single shot for use on my skiff but haven't done it yet (as a permitted guide, my permit would probably be at risk if I started any direct action..). I have seen one python that was easily nearing 20 feet long and I have seen video of a careless snake handler that almost lost a battle with with a bit smaller specimen so the potential threat is real enough... For those who've never been down my way, I'm not in the "freshwater, sawgrass, and alligators" part of the 'glades (that's only about 2/3 of the Park). Where I am it's miles and miles of mangrove jungle wilderness with lots of small bays, creeks, rivers and all of it a long way from the boat ramp.... This thread shows a chart of part of it....
http://www.charts.noaa.gov/OnLineViewer/11432.shtml
the coastline shown is 21 miles over the water from nearest facility.... Friends of mine report that the darned animals have spread now throughout the 'glades where they have no natural enemies at all. I haven't seen even a single rabbit along the only road in the Park since 2005 and figure the snakes got them all.... By the way the recent highly publicized "python hunt" was never allowed in the Park -where 90% of the animals are....