I fancy guns that are "small" for their caliber. I have a Colt Officers ACP, Kimber Ultra Carry and Charles Daly CS, all feed my lead SWC reloads wihtout problems along with a variety of JHP (Hydrashok, Golden Saber, PMC Starfire).
The Daly CS is the newest and its been 100% out of the box for over 600 rounds of Wolf, reloads, and the above mentioned JHP. The Kimber is in my carry rotation with a set of CTC Lasergrips. I replaced the extractor and outer recoil spring on it at about 800 rounds when I started getting a few extraction and return to battery failures. No problems since.
They are much more sensitive to spring rates and need cleaning much more frequently than do the larger guns. Other than my carry guns, I just wipe them down and put them back in the safe after shooting until I get crud induced failures -- I can generally fire 3-4X as may rounds without cleaing thru full size than with the sub-compacts.
The stouter recoil also makes them much more prone to "limp wristing" failures -- a vailid concern in a carry gun where you might have to shoot one handed from a less than optimum position.
Basically I'd not give a blanket recomendation for or against them, but if it means having a gun instead of the 5" in the safe, weighing the various risk factors is your decision. They work for me, although my carry is probably 50% S&W SC360 "Scandium" .357 (also with CTC Lasergrips), 40% Kahr PM40 (night sights), 5% Kimber Ultra Carry, and 5% Kel-Tec P3AT.
I also have a good assortment of double stack 45ACP guns, these are the ones I'd have concerns about carrying -- the mags are very sensitive to spring strength and dirt/crud at the single to double stack transition region which leads to "bolt over base" (aka ride over feed) failures. With the strongest mag springs I can get and keeping the mags clean they are great fun at the range, but would be amoung my last choices for carry. I have confidence it the guns, but not the mags, maybe now that the AWB is expired, the mag situation will improve -- three new 13-round Mec-Gars functioned 100% out of the box in my Para P14 so I have hope.
--wally.