When a person tries to kill you, you don't (and really shouldn't) worry about their safety. I have no remorse for a person who'd intentionally harm an innocent, and they definitly don't care about your life. If I find a man crawling through my kitchen window, he's getting shot. It's his own fault, I didn't ask him to break into my home. And for all I know he has incredible pain tolerance, so shooting him anywhere else might be a bad idea. You can't reason with the unreasonable (obviously...), so there's no point trying to talk to him. It's better to risk the life of a lunatic criminal than to risk the life of myself (the victim), my grandmother (also a victim) and anyone else that's in my house.
If a man breaks into another's home and gets shot, he brought it upon himself.
Do unto others.
I'm a huge fan of pistols of all kinds, it's hard to nail down a favorite. I like 1911s, Browning HPs, CZ-75s, VP-70s, USPs, Colt SAAs, Colt Pythons, and you just gotta love the noisy cricketts...for they are cute.
I'm also a fan of lever action rifles in pistol calibers.