You may want to check with Hamilton Bowen(Bowen Classic Arms). He does custom work on No. s and doe British big bore chamberings in them.
Won't be inexpensive, but his work is reputed to be world-class. I have seen a couple of the custom Ruger single actions he's done and the workmanship was phenomenal
Just about any competent 'smith can do it - I helped my Dad (he's the smith - not me!) do one in .416 Rigby a few years ago. Plan on a pretty big cost, as the smith will have to factor in the cost of the reamer if he doesn't have one in your chosen caliber.
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