First pistol I ever shot was a Glock 17, rented at a range. I liked it okay, it shot well. Unloaded, it felt too light, unbalanced in my hand. Loaded, the feel was better, but still imperfect. If you're gonna lug a gun around on a belt holster for a 12 hour shift though, I can see the advantage of a light, polymer framed gun.
The first pistol I ever bought was a Sig 226 in 9mm. I'd hefted a Glock, a Beretta, and a S&W, and none of them felt right in my hand the way the Sig did. Also, I have wide hands and stubby fingers; my whole hand fits on the Sig's grip, but the controls are easy to manipulate. Mostly, the Sig had a heft to it that I liked. It fit what I was looking for in a gun.
I don't carry the Sig, as I live in a state (and specifically, in a certain county) where only those who know the right people can get a CCW. However, the Sig is the gun that lies beside my bed at night, and it's the first thing I reach for if something wakes me up.