I bought my wife the SR9c as she liked that the best. I carry the G26 and G19 the most so I did have a pretty good comarision. I think it really comes down to how it feels in the hand, but the Glock will have more immediate accessories and the Ruger mags are way expensive. I won't own a pistol with less than a half-dozen mags and I picked up a few more for the wife and it wasn't cheap
Additionally, the finger base on the short magazine is nice, but adds length without capacity...I would expect in the future a similar finger extension that would be a +1 or +2. The mag sleeve for the full size SR9 mags is another good option.
The sight bases don't seem to be standard. The stock sights are fine, but if you wanted night sights, I don't think anything is on the market yet.
As to the safety, I would just ignore it and leave it off. It is easy enough to operate and my wife likes it, but it's something you can just ignore and leave off. My wife really likes the chamber indicator...I think it's a tad too big, but it could be removed if it was much of a concern. The tirgger itself is mediocre and much like most plastic striker fired triggers; I've been told it gets better over time, but it's acceptable and not too different from my Glocks.
I wish she would have selected a Glock 26 or 19 as I have plenty of parts and spare mags, but in the end, it's her handgun and one she likes and will shoot/carry. I can say it's well built (it's the stainless slide model) and it's been very reliable and good accuracy; the price was quite attactive and Ruger does have a very good customer service reputation.
ROCK6