Congrats on what is arguably the best 10 mm combat handgun available!
For ammo, you've got to try Double Tap! They offer a wide range of high performance 10 mm loadings. I'm not a hunter, so my favorite DT ammo is the 135 gr, 1600 fps, 767/ft lbs Nosler! That performance is square in .357 magnum territory, in a fast, frangible self-defense load. For hunting, look at the 200 gr hard-cast loadings. The "Four Pack" is a good deal, and lets you try several ammo-types for a flat price.
http://www.doubletapammo.com/php/catalog/index.php
I agree on swapping out the cheesy stock Glock sights. Whether you go with night sights or iron, AmeriGlo offers an excellent selection and great customer service:
http://ameriglo.com/
As for the gun, it's a Glock! I own three, and I'm spoiled silly by the lack of problems! My G21 has over 9000-rounds through it--1200 of those are 10 mm from a KKM Caliber Conversion Barrel. Our two 9 mms have given flawless performance.
If you're going to use the gun for SD/HD, consider a quality weapon light, laser designator, night sights, appropriate ammo, and additional magazines.
I always add a "butt plug" and new sights...
Bar-Sto, Storm Lake, KKM and Lone Wolf offer excellent aftermarket barrels for shooting naked lead and reloads...
Every Glock owner should know about Lone Wolf Distributors:
http://www.lonewolfdist.com/
Good luck!
Let us know how it goes!
--Ray