Great info here...now what type of .380 acp would make the best CC for my wife?
As someone else already said, you'd be better off posting this as your own question. However, before you do, use the search feature and see what's already been posted on this subject. Might already be a lot of useful informaion out there.
That said, pardon me if I hijack this thread a wee bit. (Don't be surprised if this comment ends up edited out by a moderator as such.)
In general, what your wife would find best suited for any gun, not just the .380, is what anybody else would find. And this applies even to the .22 rifle and scope that the OP posted in this string, so I suppose this MIGHT be considered slightly on-topic...
(I know, I'm stretching here.)
1. It has to fit her hand. If it's not comfortable, she's not going to like it no matter how nice a gun it might be. Which means she won't want to shoot it and she won't want to carry it.
2. It has to be easy to aim and shoot for her. By this I mean it can't be something that makes her position her hands in an unnatural or uncomfortable way in order to obtain and hold a sight picture. If it is...again, she won't want to shoot or carry it.
3. The operation of the gun has to be something she's either comfortable with or that she can easily learn. If it requires hand/body strength she doesn't have to rack the slide, for example, or even load the magazines, then it ain't gonna work for the same reasons I outlined above. Some difficulties can be oversome with reasonable training and practice. Some never are overcome for a combination of many reasons.
All these things I cited are NOT limited to women...they apply to everybody, regardless of gender, age, size, or physical limitations and regardless of what the gun is...the .22 rifle/scope the OP asked about or the .380 question you have.
I strongly advise taking anybody who wants a new gun, especially one for self-defense or home-defense, out to handle and actually shoot a variety of guns and let THEM decide.
I just bought my wife a Walther PPK/S in .380, knowing she'd be thrilled because she's a huge Bond fan and the PPK/S is one of the well known Bond guns. She was going to like this gun regardless...and she does.
However, as a self-defense weapon she's nowhere near able to handle it properly simply because the physical act of racking the slide is exceptionally difficult for her. At this time, the PPK/S would absolutely suck as a self-defense pistol for her. I fully expect her to overcome this eventually because it's simply not in her nature to NOT go out and shoot HER Bond gun. There are a number of other .380 pistols out there which would probably be more suited as a self-defense gun for such as my wife.