Install (or have installed) a free spin pawl.If the cylinder rolls past that lock point, you cant bring it back, and either have to go all the way around again, or in the case of some rounds, the case was enough out of the cylinder that it wouldn't rotate past the frame, and it wouldn't go back, and you couldn't push it in.
It happened more with the 9mm rounds in my gun and I actually had to pop the pin and cylinder out of the gun to clear it.
I picked up a Bisley last year and love it! .45ACP/ .45LC.One of these may very well be next on the list stainless Bisley. Beautiful. I’m leaning to the Blackhawk for the adjustable sights but I wouldn’t kick a vaquero outta bed for eating crackers. The loop off the grip is a nice touch.
Edit: Who made your grips?